Cholecystokinin-Like Peptide (DSK) in Drosophila, Not Only for Satiety Signaling
نویسندگان
چکیده
Cholecystokinin (CCK) signaling appears well conserved over evolution. In Drosophila, the CCK-like sulfakinins (DSKs) regulate aspects of gut function, satiety and food ingestion, hyperactivity and aggression, as well as escape-related locomotion and synaptic plasticity during neuromuscular junction development. Activity in the DSK-producing neurons is regulated by octopamine. We discuss mechanisms behind CCK function in satiety, aggression, and locomotion in some detail and highlight similarities to mammalian CCK signaling.
منابع مشابه
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عنوان ژورنال:
دوره 5 شماره
صفحات -
تاریخ انتشار 2014